This report anchors NbS as a foremost approach to drive transformation across society, addressing interwoven global crises and restoring our relationship with nature. Drawing on scientific and policy advancements, insights from ENACT partners and global NbS leaders, and analysis of mature and scaling NbS initiatives across different systems and geographies, this report explores the core enablers to scale up NbS. It also presents system-specific acceleration pathways across six implementation domains – all framed under a set of key tenets for enhancing the transformative potential of NbS.